Food, Beverage, Pharmaceutical & Dietary Supplements

Weck Laboratories has expanded the suite of tests offered for contaminants in food products including produce, fish tissue, pharmaceutical formulations, nutritional supplements and raw materials.

Our advanced instrumentation that includes multiple units of triple quadrupole LC/MS, triple quadrupole GC/MS and ICP-MS, combined with powerful sample preparation instrumentation and techniques including microwave digestion, Accelerated Solvent Extraction (ASE), Solid Phase Extraction (SPE), Solid Phase Microextraction (SPME) and automated Gel Permeation Chromatography (GPC) cleanup provides the tools to perform a whole range of testing capabilities to detect contamination on these products and verify compliance with current regulations.  In addition to our custom method development services, Weck Labs offers the following validated tests:

  • Elemental Impurities by ICP-MS USP <232>/<233>:  This test determines trace amounts of heavy metals on pharmaceutical, drug products and nutritional supplements to establish compliance.  Read more…
  • Arsenic Speciation by LC-ICP-MS:  Arsenic typically exists as different species, with each species exhibiting different levels of toxicity, making it important to differentiate them.  Five of the most common species (As3+, As5+, MMA, DMA, and AsB) are separated by liquid chromatography and detected by ICP-MS. This method is applicable to a variety of matrices, including water, juices, rice, and other products.  Read more…
  • Selenium Speciation:  Selenium exists as different species with differing levels of toxicity (Se4+ and Se6+).  These are also separated by liquid chromatography and detected by LC-ICP-MS.  Read more…
  • Methyl Mercury by LC-ICP-MS: Alkyl mercury is significantly more toxic than inorganic mercury, and is typically found in products derived from fish products.  Methyl mercury is separated from inorganic mercury (Hg2+) by liquid chromatography and detected by ICP-MS.  Read more…
  • Multi-Residue Pesticide Screen by GC-MS/MS: The analysis covers organochlorine, organophosphorus, triazine and pyrethroid pesticides in liquid matrices—water, juice, etc.—or solid matrices—produce, herbs, tablets, animal tissue, etc.
  • Multi-Residue Pesticide Screen by LC/MS: this technique covers a very high number of pesticides that are generally not amenable to analysis by traditional techniques (GC or GC-MS). Our new state-of-the-art LC-MS/MS can screen for over two hundred pesticides in many matrices.
  • Polynuclear Aromatic Hydrocarbons (PAHs) in food products: PAHs are analyzed by triple quadrupole GC-MS/MS at very low levels in a variety of matrices, including fish and plant tissues, and pharmaceutical formulations.
  • Residual Solvents:  Analysis of solvents in pharmaceutical products by USP <467> is performed using headspace and GC/MS to detect the target solvents.  Additionally, this technique can identify unknown or non-target solvents in pharmaceutical formulations.
  • Cleaning Validation for production equipment at pharmaceutical facilities: this test is performed by analyzing Total Organic Carbons on swabs from equipment.
  • Microbiological Testing in juice and food products: Analysis of salmonella, total coliforms, e. coli, fecal coliforms, bacterial speciation, streptococcus and enterococcus.
Back To Top